Supporting diagnosis of neurological diseases - primarily motor neuron disease and motor neuropathies.
99% of normals fall below these titers: IgG Monosialo GM1 <1:500, IgM Monosialo GM1 <1:1000, IgG Asialo GM1 <1:4000, IgM Asialo GM1 <1:4000, IgG Disialo GD1b <1:1000, IgM Diasialo GD1b <1:1000.
Titer values of 1:250-1:2000 (modest elevations) are found in 5% of patients with motor neuron disease. Patients with ALS may have modest elevations. High titers have been found only in patients with multifocal motor neuron neuropathy.
3 - 15 days
- Monosialo GM1 Antibodies
- Asialo GM1 Antibodies
- Disialo GD1b Antibodies
- Co-GM1 Triad Antibody Test
- Motor Neuropathy Antibody
Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
Screening tests are performed for IgG and IgM antibodies to GM1 and GD1b. If positive, the appropriate titer will be performed at an additional charge. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test sent to Mayo Medical Laboratories.