Test Overview
Test Methodology


Test Usage

Establish the presence of filamentous fungi, dimorphic pathogens, Candida species and aerobic actinomycetes.

Reference Range *

No fungi or aerobic actinomycete isolated.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

A single negative culture does not rule out the presence of fungal infection. Optimal isolation of fungi from tissue is accomplished by processing as much tissue as possible for culture.

Test Details
Days Set Up
Analytic Time

Preliminary results on all cultures are reported in 12-24 hours. The health care provider will be notified of cultures positive with systemic pathogens. Negative cultures will be reported after 4 weeks.

Soft Order Code
MiChart Code
Fungus Smear Only
  • Biopsy, Fungus Culture
  • Culture, Tissue, Fungus
  • Deep Tissue, Fungus Culture
  • FNG
  • Fungus Culture Biopsy
  • Tissue Culture, Fungus
  • Surgical Specimen, Fungus Culture
  • Nocardia Culture, Tissue
Specimen Requirements
Collection Instructions

Collect tissue into a sterile container with 0.5 ml sterile saline following sterile preparation of biopsy site. DO NOT SEND SWABS. The portion of the surgical specimen submitted for this test should be separated from the portion submitted for other testing. For optimum recovery, send immediately. If specimen must be stored and Histoplasma isolation is not desired, refrigerate immediately after specimen collection. May be refrigerated up to 24 hrs. If Histoplasma isolation is desired, keep specimen at room temperature and send within 4 hrs of specimen collection. If Histoplasma or other fungal species is suspected, indicate on requisition. Indicate specimen source, collection date/time, current antibiotic therapy, and clinical diagnosis. If an unacceptable specimen is received, the client will be notified and another specimen will be requested before disposal of the specimen.

Normal Volume
As much as possible in sterile container
Minimum Volume
As much as possible in sterile container
Additional Information

Test includes culture and, if specimen is adequate, direct smear. Isolation of Histoplasma is suboptimal from specimens older than 4 hrs and is unlikely from specimens older than 8 hrs. Decreased isolation of filamentous fungi from specimens received on swabs, tissue or fluid is preferred.

CPT Code
87102 Isolation, 87106 Identification, 87205 Smear
Fee Code