Establish the presence of filamentous fungi, dimorphic pathogens and aerobic actinomycetes.
No fungi or aerobic actinomycete isolated.
Isolation of Histoplasma is suboptimal from specimens older than 4 hrs and is unlikely from specimens older than 8 hrs or from specimens that have been refrigerated.
Preliminary results on all cultures are reported in 12-24 hours. The health care provider will be notified of positive cultures. Negative cultures will be reported after 4 weeks.
- Candida, CSF
- Cryptococcus, CSF
- CSF, Fungus Culture
- Culture, CSF, Fungus
- Fungus Culture, Cerebrospinal Fluid
- Spinal Fluid, Fungus Culture
- FUNGUS CULTURE/SMEAR
- Nocardia Culture, CSF
Clinical neurological diagnosis must be noted on the requisition for processing. Please contact MLabs at 800-862-7284 to request smear only or culture for Histoplasma, Blastomyces, or Coccidioides. Fungal cultures are not routinely performed on cerebrospinal fluid due to the low probability of recovery of molds. CSF is the specimen of choice for detection of cryptococcal meningitis in adults and Candida meningitis in children. Cryptococcus antigen test will be performed when CSF is received for suspected cryptococcal meningitis. Candida species will grow on routine (aerobic) CSF culture. Collect specimen after sterile preparation of aspiration site. For optimum recovery, send immediately. If specimen must be stored and Histoplasma isolation is not desired, refrigerate immediately after specimen collection. May be refrigerated up to 24 hrs. If Histoplasma isolation is desired, keep specimen at room temperature and send within 4 hrs of specimen collection. Indicate specimen source, collection date/time, current antibiotic therapy and clinical diagnosis on requisition. If an unacceptable specimen is received, the client will be notified before disposal of the original specimen.
Test includes culture and, if specimen is adequate, direct smear. Cryptococcal antigen testing will be performed at an additional charge on all CSF specimens submitted for fungal culture. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.