Test Overview
Immunoassay
This assay detects Filaria IgG4 associated with infections caused by the major filarial parasites, including Dirofilaria immitis, Wuchereria brancrofti, Brugia malayi, and Onchocerca volvulus.
Chronic filarial infections manifesting as elephantiasis may not show a significant IgG4 response and cannot be ruled out using this test. Samples containing antibodies to other nematodes,
particularly Strongyloides, may cross-react in the assay.
<2.50 index
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
This assay was developed for the detection of IgG4 subclass antibody to enhance specificity without sacrifice of sensitivity. Antigens of Dirofilaria immitis are employed that serologically crossreact with all filarial species, including W. bancrofti, B. malayi and O. volvulus. Chronic elephantiasis may not result in a significant IgG4 antibody response and cannot be ruled out by this test.
Test Details
4 - 22 days
- Microfilaria Antibody
- Brugia sp. Antibody
- Wuchereria bancrofti Antibody
- Onchocerca volvulus Antibody
- Mansonella Antibody
- Loa loa Antibody
Specimen Requirements
Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
Additional Information
Test sent to Mayo Medical Laboratories; performed by Quest Diagnostics.