Test Overview
Test Methodology

Liquid Chromatography - Tandem Mass Spectrometry (LC-MS/MS)

Test Usage

Fentanyl is potent synthetic opioid analgesic that is used for chronic pain and as an anaesthetic. It has about 100 times the potency of morphine and 50 times that of heroin. Measurement of Fentanyl, and its metabolite Norfentanyl, in urine by UPLC-MS/MS can give clinicians valuable information with regard to monitoring Fentanyl use in pain management. Also, urine levels are important in cases of Fentanyl abuse or overdose.

Reference Range *

Negative. Fentanyl: <1.0 ng/mL; Norfentanyl: <10.0 ng/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Varies (minimum once per week)
Analytic Time

8 hours

Soft Order Code
MiChart Code
Fentanyl, Urine Quantitative
Chemical Pathology
Drug Analysis
Specimen Requirements
Collection Instructions

Collect random urine specimen in clean plastic container.

Normal Volume
3.0 mL urine
Minimum Volume
1.0 mL urine
CPT Code
Fee Code
Fentanyl: 3637-6; Norfentanyl: 11075-9