ENA (ANTI SS-A/ANTI SS-B)
EXTRACTABLE NUCLEAR ANTIBODY
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Multiplex Flow Immunoassay
SS-A (Ro) and SS-B (La) antibodies have a strong association with Sjogen’s syndrome and can be used to support the clinical diagnosis. SS-A is present in 70 - 75% and SS-B in 60 - 65% of patients with Sjogren’s syndrome. However, both SS-A and SS-B antibodies are present in SLE and other connective tissue disorders, so their presence must be interpreted in the clinical context. The BioPlex 2200 test system uses an affinity purified SS-A 60 antigen, a second SS-A 52 recombinant antigen, and an affinity purified SS-B antigen.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.