Test Overview
Test Methodology

Multiplex Flow Immunoassay

Test Usage

SS-A (Ro) and SS-B (La) antibodies have a strong association with Sjogen’s syndrome and can be used to support the clinical diagnosis. SS-A is present in 70 - 75% and SS-B in 60 - 65% of patients with Sjogren’s syndrome. However, both SS-A and SS-B antibodies are present in SLE and other connective tissue disorders, so their presence must be interpreted in the clinical context. The BioPlex 2200 test system uses an affinity purified SS-A 60 antigen, a second SS-A 52 recombinant antigen, and an affinity purified SS-B antigen.

Reference Range *

Negative

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

1 day

Soft Order Code
SSAB
MiChart Code
Extractable Nuclear Antibodies, SS-A and SS-B
Synonyms
  • ROLA
  • Anti-Ro (SSA)
  • Anti-SSB (La)
  • Anti-SSA (Ro)
  • ANTI-SSB/ANTI-LA
  • SSASSB
  • ENA (ANTI SS-A/ANTI SS-B)
  • SS-A
  • ANTI-SSA/ANTI-RO
  • La Antibody
  • Ro Antibody
  • SS-A Antibody
  • SS-B
  • SS-B Antibody
  • Anti-La (SSB)
  • Sjogren's Antibodies
  • EXTRACTABLE NUCLEAR ANTIBODY
  • SSA
  • SSB
  • SSAB
Laboratory
Chemical Pathology
Section
Immunopathology
Specimen Requirements
Collection Instructions

Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Alternate Specimen
Red top tube.
Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL serum
Additional Information

Panel includes SS-A (Ro) and SS-B (La) Antibodies. These antibodies may also be ordered individually.

Billing
CPT Code
86235 x2
Fee Code
20570 SSAB, 30930 SSB, 30931 SSA
LOINC
Z33-1 SSAB, 8093-7 SS-A, 8094-5 SS-B
Resources