Test Overview
Test Methodology

LC-MS/MS

Test Usage

Estrogens are important in the development and maintenance of the female sex organs and secondary sex characteristics. They also regulate the menstrual cycle and are important in the maintenance of pregnancy. Estradiol is the most potent naturally occurring estrogen. Estradiol is normally metabolized into estrone, which in turn can be metabolized along two alternative pathways eventually to either estriol or 2-methoxyestrone. The direction of estradiol metabolism is altered in hyperthyroidism and anorexia nervosa in increased formation of 2-hydroxyestrone and subsequently 2-methoxyestrone. This causes a consequent decrease in the formation of estriol.

Reference Range *

Age and sex specific reference ranges provided with report. Includes Estrone (E1) and Estradiol (E2).

Test Details
Days Set Up
Monday - Saturday
Analytic Time

2 - 4 days

Soft Order Code
ESTF
MiChart Code
Estrogens, Fractionated
Synonyms
  • ESTF
  • Estrogens, E1+E2, Fractionated
Laboratory
Sendout
Reference Laboratory
Mayo ESTF (84230)
Section
Special Testing
Specimen Requirements
Collection

Collect specimen in red top tube; do not use SST tube. Centrifuge and aliquot serum into a plastic vial within 2 hours of collection. Refrigerate.

Rejection Criteria
SST tube not acceptable.
Yellow Top Tube
Red Top Tube
Normal Volume
1.2 mL serum
Minimum Volume
0.8 mL serum
Additional Information

Test sent to Mayo Medical Laboratories.

Billing
CPT Code
82670, 82679
Fee Code
31506
LOINC
2254-1
NY State Approved
No