Update Type: Test Methodology Changed
Test Updated: 02/21/2024
Test Overview
Test Methodology

Polymerase Chain Reaction (PCR)

Test Usage

The QEBV assay is intended for use as an aid in the management of EBV in transplant patients. In patients undergoing monitoring of EBV, serial DNA measurements can be used to indicate the need for potential treatment changes and to assess response to treatment.

Reference Range *

Not Detected. The reportable range of the assay is from:
35 I.U./mL (Log10 1.54 I.U./mL) to 100,000,000 I.U./mL (Log10 8.0 I.U./mL)
Virus that is detectable at levels above or below the reportable range will be reported but not quantified. The analytical limit of detection of the assay is 18.8 (log10 1.27) IU/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

The results are intended to be read and analyzed by a qualified licensed healthcare professional in conjunction with clinical signs and symptoms and relevant laboratory findings. Negative test results do not preclude EBV infection or EBV disease. Test results must not be the sole basis for patient management decisions.

Test Details
Days Set Up
Tues, Thurs, Sat
Analytic Time

Performed Tu, Th, Sat. 6 hours analytic time.

Soft Order Code
MiChart Code
Epstein-Barr Virus DNA, Quant, Plasma (In-House)
  • QEBV
  • EBV Viral Load, Plasma
Specimen Requirements
Collection Instructions

Collect specimen in a 6 ml lavender top (EDTA) tube. Centrifuge for 20 minutes at 800 - 1600 xg at room temperature and aliquot plasma into a polypropylene plastic vial within 24 hours of collection. Refrigerate for up to 6 days or freeze for longer storage. Do not allow frozen specimens to thaw at any time during storage or transport, due to possible degradation of the viral load. Microbiology molecular testing requires a dedicated sample, and cannot be shared with other laboratories.

Normal Volume
4 mL whole blood or 2 mL EDTA plasma
Minimum Volume
2 mL whole blood or .75 mL EDTA plasma
CPT Code
Fee Code