Multiplex Flow Immunoassay
Support diagnosis of EBV infection.
NEGATIVE: Indicates no detectable IgM antibody to EBV Viral Capsid Antigen; EQUIVOCAL: Presence or absence of IgM antibody to EBV Viral Capsid Antigen cannot be determined. Another specimen should be sent for analysis; POSITIVE: Indicates detectable levels of IgM antibody to EBV Viral Capsid Antigen.
Assay performance characteristics have not been established for immunocompromised or immunosuppressed patients, cord blood, neonatal specimens or infants. Assay performance characteristics have not been established for the diagnosis of nasopharyngeal carcinoma, Burkitt’s lymphoma and other EBV-associated lymphomas.
- EBV Viral Capsid AG, IgM
Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
IgM antibodies to VCA are normally present in acute IM and generally absent in convalescence. A rise is indicative of an acute stage of infection or reactivation. The presence of antibodies in otherwise healthy individuals usually indicates immunological exposure either as silent primary infection or reactivation. Antibody levels tend to rise and peak after 3-4 weeks, then decline and usually dissipate after 2-3 months.