Multiplex Flow Immunoassay
Support the diagnosis of EBV infection.
NEGATIVE: Indicates no detectable IgG antibody to EBV Viral Capsid Antigen; EQUIVOCAL: Presence or absence of IgG antibody to EBV Viral Capsid Antigen cannot be determined. Another specimen should be sent for analysis; POSITIVE: Indicates detectable levels of IgG antibody to EBV Viral Capsid Antigen.
Assay performance characteristics have not been established for immunocompromised or immunosuppressed patients, cord blood, neonatal specimens or infants. Assay performance characteristics have not been established for the diagnosis of nasopharyngeal carcinoma, Burkitt’s lymphoma and other EBV-associated lymphomas.
- EBV Viral Capsid Ag, IgG
Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
IgG antibodies to VCA are normally present in acute and convalescent IM. A rise is indicative of an acute stage of infection. The presence of antibodies in otherwise healthy individuals usually indicates immunological exposure either as silent primary infection or past exposure. Antibody levels tend to rise and peak after 3-4 weeks, then decline and usually persist for life.