Multiplex Flow Immunoassay
Support diagnosis of EBV infection.
NEGATIVE: Indicates no detectable IgG antibody to EBV Nuclear Antigen; EQUIVOCAL: Presence or absence of IgG antibody to EBV Nuclear Antigen cannot be determined. Another specimen should be sent for analysis; POSITIVE: Indicates detectable levels of IgG antibody to EBV Nuclear Antigen.
Assay performance characteristics have not been established for immunocompromised or immunosuppressed patients, cord blood, neonatal specimens or infants. Assay performance characteristics have not been established for the diagnosis of nasopharyngeal carcinoma, Burkitt’s lymphoma and other EBV-associated lymphomas.
- EBV Nuclear Ag, IgG
IgG antibodies to EBNA-1 are rarely present in acute IM and normally rise during convalescence. A rise may be indicative of progression from early to later stages of convalescence. The presence of antibodies in otherwise healthy individuals usually indicates past exposure. Antibody levels will rise to a plateau level in three months to a year and will normally persist for life.