Reverse Transcription Polymerase Chain Reaction (RT-PCR)
Detection of Enterovirus meningitis.
Enterovirus RNA not detected.
A positive EV result does not rule out other causes of meningitis, including bacteria, mycobacteria, or other viruses (e.g., herpes family viruses, arboviruses, mumps virus, etc.) and fungi. Rare occurrences of simultaneous mixed bacterial-viral meningitis have been reported in the literature. False positive results are possible. Negative test results do not rule out the presence of enterovirus. Interfering endogenous substances encountered in CSF could cause false negative results.
- ENTEROVIRUS, QUALITATIVE; PCR
- Coxsackie B
- Coxsackie A
- Enterovirus by Rapid PCR
- EV RNA detection by PCR
- Enterovirus meningitits detection by PCR
Collect spinal fluid. Refrigerate up to 24 hours or freeze for longer storage. Do not centrifuge.
The Enterovirus RT-PCR uses the reverse transcriptase polymerase chain reaction to amplify Enterovirus-specific RNA sequences directly from the patient's CSF. Results should be used in conjunction with other laboratory test results and the patient's clinical profile.