Test Overview
Test Methodology

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Test Usage

Therapeutic drug monitoring.

Reference Range *

Encainide: 15 - 100 ng/mL; O-desmethylencainide (ODE): 100 - 300 ng/mL; 3-methoxy-ode (MODE): 60 - 300 ng/mL. Ten percent of patients do not form therapeutic levels of the active metabolites MODE and ODE. In these patients, the recommended range for encainide is 300 - 1,200 ng/mL.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

4 - 8 days

Soft Order Code
FENC
MiChart Code
Encainide (Enkaid), Level
Synonyms
  • Enkaid
  • ENCAINIDE (ENKAID)
  • ENCAINIDE
  • MODE
  • ODE
  • 3-METHOXY-ODE (MODE)
  • O-DEMETHYLENCAINIDE (ODE)
Laboratory
Sendout
Reference Laboratory
Mayo FENC (90087) (MedTox 176)
Section
Special Testing
Specimen Requirements
Collection Instructions

Collect blood in a red or green top tube; do not use SST tube. Centrifuge, aliquot serum or plasma into plastic vial and refrigerate.

Rejection Criteria
SST or PST tube not acceptable.
Yellow Top Tube
Red Top Tube
Normal Volume
1.0 mL heparinized plasma or serum
Minimum Volume
0.25 mL heparinized plasma or serum
Additional Information

Test sent to Mayo Medical Laboratories; performed by MedTox Laboratories.

Billing
CPT Code
80375
Fee Code
20042
LOINC
Z328-5
NY State Approved
No
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