Test Overview
ELISA
Pancreatic elastase (PE) is not degraded during intestinal transit and the concentration of PE in a stool sample reflects exocrine pancreatic function. This assay allows the diagnosis or exclusion of pancreatic exocrine insufficiency, which can be caused by chronic pancreatitis, cystic fibrosis, pancreatic tumor, cholelithiasis or diabetes mellitus.
Normal: >200 mcg Elastase/g; Moderate to slight exocrine pancreatic insufficiency: 100 - 200 mcg/g Elastase; Severe exocrine pancreatic insufficiency: <100 mcg Elastase/g.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
A watery, diarrheal stool is not recommended for this test as some dilutions during the assay may give lower E1 concentrations than are actually present.
Test Details
4 - 7 days
- Trypsinogen, Stool
- Stool, Trypsin
- Fecal Trypsin
- Chymotrypsin
- Pancreatic Elastase, Stool
- ELASTF
- Elastase, Stool
Specimen Requirements
Collect random stool specimen and freeze. Pancreatic enzyme supplementation therapy should be discontinued prior to sample collection.
Additional Information
Test performed by Mayo Clinic Laboratories