Test Overview
Test Methodology

Hemolysis

Test Usage

To rule out the diagnosis of paroxysmal cold hemoglobinuria (PCH) in cases of hemoglobinuria, cold exacerbated hemolysis, unusual presentation of apparent warm or cold autoimmune hemolytic anemia (AIHA). A positive test is considered diagnostic for PCH.

Reference Range *

Interpretive report provided under Immunohematology Consult.

Test Details
Days Set Up
Monday - Friday
Analytic Time

1 Day

Soft Order Code
DLINT
MiChart Code
DL INTERP
Laboratory
Blood Bank
Reference Laboratory
N/A
Section
Blood Bank
STAT Availability

Testing time is 5 hours for initial result. Blood Bank Pathologist performs a clinical review found in the Immunohematology Consult Report.

Specimen Requirements
Collection

Collect samples and immediately store in 37 C warm sand for transport to Blood Bank.
Warm sand thermos is available in Chemistry.

Collection Instructions

See Donath Landsteiner Test for Outpatients

Special Handling

Collect samples and immediately store in 37 C warm sand for transport directly to Blood Bank.
Warm sand thermos is available in Chemistry.
Samples must be received in Blood Bank by 12 noon for same-day processing.

Alternate Specimen
N/A
Normal Volume
8 mL serum
2 mL EDTA whole blood
Minimum Volume
4 mL serum
1 mL EDTA whole blood
Storage Temperature
Store at 37 C immediately after collection.
Store at 4 C after separating serum from cells.
Rejection Criteria
Samples displaying hemolysis, collected in serum separator tubes, contaminated, of inadequate volume or not properly identified will be rejected.
Billing
CPT Code
86941
Fee Code
21259
LOINC
18787-3
NY State Approved
No