Test Overview
Optical determination of clotting time after addition of snake venom reagent (DRVVT). If result is elevated, a second reagent is added that contains higher concentration of phospholipid (DRVRA).
Detection of phospholipid antibody (lupus anticoagulant) in plasma.
DRVVT <44 seconds; DRVVT Ratio <1.25
- *Reference ranges may change over time.
- Please refer to the original patient report when evaluating results.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Test Details
1 hour
- Dilute Venom Time
- DRVVT
- Russell's Viper Venom Test
- Venom Time
- DRVVT PT
- DRVVT CONT
- DRVVT RAT
- DRVVT PATIENT SECONDS
- DRVVT CONTROL SECONDS
- DRVVT RATIO
- DILUTE RUSSELL'S VIPER VENOM
- DRVVT PT
- DRVVT RAT
- LA CONFIRM
- DRVVT PATIENT SECONDS
- DRVVT RATIO
- Phospholipid Antibody (Lupus Anticoagulant)
Specimen Requirements
Collect specimen in a blue top (citrate 3.2%) tube. Mix by inversion. Specimen should arrive at lab within 3 hours of collection; transport at room temperature. Alternatively, centrifuge, aliquot plasma into a plastic vial, and freeze the specimen within 4 hours of collection. Transport frozen specimen on dry ice. Collection of the blood through lines that have been previously flushed with heparin should be avoided. If the blood must be drawn through a VAD (vascular access device), the line should be flushed with 5 mL of saline and the first 5 mL of blood or six dead space volumes of the VAD discarded.
Additional Information
Phospholipid antibodies are associated with a variety of clinical conditions, including thrombosis, throbocytopenia, and fetal loss. They are also present in individuals with SLE, rheumatoid arthritis, and other autoimmune diseases. Transient development of lupus anticoagulants is common with viral infections and certain drug therapies.