Test Overview
Test Methodology
Real-Time Polymerase Chain Reaction (PCR) with Allelic Discrimination Analysis
Test Usage
This is a pharmacogenomics test associated with 5-fluorouracil and capecitabine drug sensitivity. Biallelic variation in the DPYD gene is also associated with dihydropyrimidine dehydrogenase (DPD) deficiency.(1) Individuals who have variations identified in the DPYD may benefit from genetic consultation
Reference Range *
Interpretive report provided
Test Details
Update Type: Replacement Test
Test Updated: 05/26/2021
Days Set Up
Monday - Friday
Analytic Time
4 - 12 days
Soft Order Code
DPYDQ
MiChart Code
DPYDQ
Laboratory
Sendout
Reference Laboratory
Mayo DPYDV
Section
Special Testing
Specimen Requirements
Collection
Collect blood in EDTA lavender top tube. Send to Specimen Processing ambient. Saliva collection kit is to be collected per kit instructions and sent to Specimen Processing ambient. DNA should be shipped frozen
Special Handling
DNA concentration request is 100 mcL at a concentration of 50 ng/mcL
Normal Volume
3 mL blood, 1 swab, 100 mcL DNA
Minimum Volume
Blood 0.4 mL, 1 swab, 100 mcL DNA
Additional Information
Test performed by Mayo Clinic Laboratories
Billing
CPT Code
81232
NY State Approved
No