Test Overview

Test Methodology

Real-Time Polymerase Chain Reaction (PCR) with Allelic Discrimination Analysis

Test Usage

This is a pharmacogenomics test associated with 5-fluorouracil and capecitabine drug sensitivity. Biallelic variation in the DPYD gene is also associated with dihydropyrimidine dehydrogenase (DPD) deficiency.(1) Individuals who have variations identified in the DPYD may benefit from genetic consultation

Reference Range*

Interpretive report provided

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details

Days Test Performed

Monday - Friday

Analytic Time

4 - 12 days

Soft Order Code


MiChart Code




Laboratory Reference


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Specimen Requirements

Special Handing

DNA concentration request is 100 mcL at a concentration of 50 ng/mcL

Normal Volume

3 mL blood, 1 swab, 100 mcL DNA

Minimum Volume

Blood 0.4 mL, 1 swab, 100 mcL DNA

Additional Information

Test performed by Mayo Clinic Laboratories

Billing Information

Fee Codes

CPT Code


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