Update Type: Test Code Change
Test Updated: 10/18/2023
Test Overview
Test Methodology

Real-Time Polymerase Chain Reaction (PCR) with Allelic Discrimination Analysis

Test Usage

This is a pharmacogenomics test associated with 5-fluorouracil and capecitabine drug sensitivity. Biallelic variation in the DPYD gene is also associated with dihydropyrimidine dehydrogenase (DPD) deficiency.(1) Individuals who have variations identified in the DPYD may benefit from genetic consultation

Reference Range *

Interpretive report provided

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

4 - 12 days

Soft Order Code
DPYDQ
MiChart Code
DPYDQ
Laboratory
Sendout
Reference Laboratory
Mayo DPYDQ
Section
Special Testing
Specimen Requirements
Collection

Collect blood in EDTA lavender top tube. Send to Specimen Processing ambient. Saliva collection kit is to be collected per kit instructions and sent to Specimen Processing ambient. DNA should be shipped frozen

Special Handling

DNA concentration request is 100 mcL at a concentration of 50 ng/mcL

Normal Volume
3 mL blood, 1 swab, 100 mcL DNA
Minimum Volume
Blood 0.4 mL, 1 swab, 100 mcL DNA
Additional Information

Test performed by Mayo Clinic Laboratories

Billing
CPT Code
81232