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Kinetic Immunoassay (KIMS)
Diagnosis of digoxin toxicity, monitor therapeutic drug level.
0.5 - 1.5 ng/mL. Note that in the setting of chronic heart failure, retrospective analysis of data from a randomized clinical trial revealed the following associations between serum digoxin concentrations and all-cause mortality: 0.5 to 0.8 ng/mL, lower risk than placebo; 0.9 to 1.1 ng/mL, similar risk to placebo; 1.2 ng/mL and above, higher risk than placebo. Critical Value: >2.0 ng/mL.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Collect blood in a red top tube. Centrifuge, aliquot serum into a plastic vial, and refrigerate. Blood specimen should be drawn at least 8 hours after the administration of the last dose (falsely elevated results may occur if blood is drawn less than eight hours after last dose).