Diagnosis of chronic granulomatous disease (CGD), X-linked and autosomal recessive forms, complete myeloperoxidase (MPO) deficiency; monitoring chimerism and NADPH oxidase function posthematopoietic cell transplantation, assessing residual NADPH oxidase activity pretransplant, and identification of carrier females for X-linked CGD; assessment of changes in lyonization with age in carrier females.
Interpretive report provided.
4 - 6 days
- Granulocyte Function Assay
- Neutrophil Function Assay
- Oxidative Burst Assay
- Chronic Granulomatous Disease (CGD) Assay
- Nitroblue Tetrazolium (NBT) Replacement Assay
- Neutrophil Oxidative Burst
Collect Monday-Thursday only. Requires a non-related control specimen to accompany specimen
MLabs clients please notify the MLabs Client Services Center prior to sending specimen. Specimens are accepted Monday - Thursday only and must be received by performing laboratory within 48 hours of collection. Specimen transport should be arranged so that the specimen is received by MLabs as close to shipping time as possible. Call for a STAT courier if necessary. Collect specimen in a green top tube. Also collect a normal control specimen in a green top tube (NOT from the patient or a family member) at the same time that the patient is drawn. Send intact whole blood stored and transported at room temperature within 24 hours of collection; do not refrigerate or freeze.
Test sent to Mayo Medical Laboratories.