Diagnosis of chronic granulomatous disease (CGD), X-linked and autosomal recessive forms, complete myeloperoxidase (MPO) deficiency; monitoring chimerism and NADPH oxidase function posthematopoietic cell transplantation, assessing residual NADPH oxidase activity pretransplant, and identification of carrier females for X-linked CGD; assessment of changes in lyonization with age in carrier females.
Interpretive report provided.
4 - 6 days
- Granulocyte Function Assay
- Neutrophil Function Assay
- Oxidative Burst Assay
- Chronic Granulomatous Disease (CGD) Assay
- Nitroblue Tetrazolium (NBT) Replacement Assay
- Neutrophil Oxidative Burst
Collect Monday-Thursday only. Specimen must be in Specimen Processing no later than 8 pm Monday - Thursday. Requires a non-related control specimen to accompany specimen
MLabs clients please notify the MLabs Client Services Center prior to sending specimen. Specimens are accepted Monday - Thursday only and must be received by Mayo within 48 hours of collection. Specimen MUST be in Specimen Processing no later than 8 pm Monday-Thursday. Specimen transport should be arranged so that the specimen is received by MLabs as close to shipping time as possible. Call for a STAT courier if necessary. Collect specimen in a green top tube. Also collect a normal control specimen in a green top tube (NOT from the patient or a family member) at the same time that the patient is drawn. Send intact whole blood stored and transported at room temperature within 24 hours of collection; do not refrigerate or freeze.
Test sent to Mayo Medical Laboratories.