Test Overview
Test Methodology

Flow Cytometry

Test Usage

Diagnosis of chronic granulomatous disease (CGD), X-linked and autosomal recessive forms, complete myeloperoxidase (MPO) deficiency; monitoring chimerism and NADPH oxidase function posthematopoietic cell transplantation, assessing residual NADPH oxidase activity pretransplant, and identification of carrier females for X-linked CGD; assessment of changes in lyonization with age in carrier females.

Reference Range *

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday at 4pm. If not received by 4pm on Friday AT MAYO, the test will be cancelled. Specimen must be in Specimen Processing no later than 8 pm Monday - Thursday.
Analytic Time

4 - 6 days

Soft Order Code
DHRP
MiChart Code
DHR Flow PMA, Blood (Sendout)
Synonyms
  • Granulocyte Function Assay
  • Neutrophil Function Assay
  • Oxidative Burst Assay
  • Chronic Granulomatous Disease (CGD) Assay
  • Nitroblue Tetrazolium (NBT) Replacement Assay
  • OXBU
  • NOXB
  • Neutrophil Oxidative Burst
  • DHRP
Laboratory
Sendout
Reference Laboratory
Mayo DHRP (62765)
Section
Special Testing
Specimen Requirements
Collection

Collect Monday-Thursday only. Specimen must be by University Hospital main laboratory Specimen Processing area no later than 8 pm Monday - Thursday. Requires a non-related control specimen to accompany specimen. Plain label the tube with the word CONTROL and the collection date and time. Use green top sodium heparin tubes only. Do not use lithium heparin tubes.

Collection Instructions

MLabs clients please notify the MLabs Client Services Center prior to sending specimen. Specimens are accepted Monday - Thursday only and must be received by Mayo within 48 hours of collection. Specimen MUST be in University Hospital main laboratory Specimen Processing area no later than 8 pm Monday-Thursday. Specimen transport should be arranged so that the specimen is received by MLabs as close to shipping time as possible. Call for a STAT courier if necessary. Collect specimen in a green top tube, sodium heparin only, do not use lithium heparin tubes. Also collect a normal control specimen in a green top tube, sodium heparin only, do not use lithium heparin tubes. (NOT from the patient or a family member) at the same time that the patient is drawn. Plain label the tube with the word CONTROL and the collection date and time. Send intact whole blood stored and transported at room temperature within 24 hours of collection; do not refrigerate or freeze.

Normal Volume
5 mL whole blood
Minimum Volume
1 mL whole blood
Storage Temperature
Strict ambient
Rejection Criteria
Specimen collected in a lithium heparin tube
Additional Information

Test sent to Mayo Medical Laboratories.

Billing
CPT Code
86352
Fee Code
AA899