Liquid Chromatography - Tandem Mass Spectrometry (LC-MS/MS)
Monitor therapeutic drug levels; monitor patient compliance; evaluate desipramine toxicity
Therapeutic: 50 - 250 ng/mL; Toxic: > 500 ng/mL.
Phenothiazines and other antidepressant drugs may interfere when administered concomitantly.
- DESIPRAMINE LEVEL
- Tricyclics, Desipramine
Collect blood in a red top or green top tube; do not use SST tube. Centrifuge, aliquot serum or plasma into plastic vial as soon as possible and refrigerate.