Anti-IIa clottable assay. This assay is able to detect dabigatran levels between 40 - 1000 ng/ml.
Used for determining dabigatran anti-IIa activity in plasma.
Normal individuals have no dabigitran activity. A correlation of anti-IIa activity and therapeutic benefit has not been demonstrated. If this test result is greater than 40 ng/mL, then the patient has some detectable anticoagulant effect from dabigatran.
- Ecarin Clotting Time
- Dabigatran Etexilate
- Anti-IIa Inhibitor Assay
STAT requests for this test will be performed on a STAT basis (supervisory staff approval is not required).
Collect specimen in a blue top (citrate 3.2%) tube. Mix by inversion. Specimen should arrive at lab within 4 hours of collection; transport at room temperature. Alternatively, centrifuge, aliquot plasma into a plastic vial, and freeze the specimen within 4 hours of collection. Transport frozen specimen on dry ice. Collection of the blood through lines that have been previously flushed with heparin should be avoided. If the blood must be drawn through a VAD (vascular access device), the line should be flushed with 5 mL of saline and the first 5 mL of blood or six dead space volumes of the VAD discarded.