Days Set Up
Monday - Friday, 8:00am - 4:00pm
Analytic Time
MiChart Code
Cytogenetics, FISH for CMA-detected Abnormality, Peripheral Blood
Soft Order Code

Test Updated:


Chromosomal Microarray Confirmation
FISH Confirmation, Parental Sample
CMA Confirmation
Parental Analysis of Chromosomal Microarray Result
Array Analysis, Parental Sampl
Parent Analysis of CMA Result
Parental FISH
FISH Analysis, Prntl Shadow
Cytogenetics, FISH for CMA Abn
Aberrant CMA confirmation by FISH
Aberrant Chromosomal Microarray (CMA) Confirmation by FISH

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Test Overview

Test Methodology

Fluorescence In Situ Hybridization (FISH)

Test Usage

FISH testing is intended to determine inheritance of an abnormal Chromosomal Microarray Analysis result on a child/proband (CMA testing available from the MMGL Molecular Genetics Laboratory). FISH analyses of peripheral blood samples from both parents of a patient with a CMA aberration are recommended to determine whether the abnormality occurred de novo or was inherited from a carrier parent. Identifying the origin of the aberration (de novo or parental) allows a better assessment of the probability that the aberration is pathogenic, promotes improved diagnosis of disease (or risk of disease), allows a more precise calculation of recurrence risk, and facilitates more accurate and appropriate counseling.

Reference Range

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Please notify MLabs Client Services Center prior to sending specimen. Requests for this test will be accepted if the CMA test was performed for the child/proband at the University of Michigan MMGL Molecular Genetics Laboratory. Collect specimen in a green top (sodium heparin) tube. Invert the tube several times to prevent clotting. Send the specimen intact at room temperature within 24 hours of collection. DO NOT CENTRIFUGE. Clotted or hemolyzed specimens are unacceptable. Include the proband's CMA information specified, as follows: Proband name, U of M registration number, chromosome abnormality (deletion or duplication), size, band, beginning and ending nucleotide numbers.

Normal Volume
5 mL whole blood
Minimum Volume
2 mL whole blood

Billing Information

CPT Code
88230, 88271, 88273 (deletion) or 88275 (duplication)
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.