Test Overview
Test Methodology

Unstimulated short term and long-term adherent cell culture and chromosome analysis. Fluorescence In Situ Hybridization (FISH) and Microarray when indicated.

Test Usage

Identification of chromosomal abnormalities to assist in classification and prognostication of malignant tumors. Most malignant neoplasms are associated with genetic changes and the observation of an abnormal cytogenetic clone is consistent with a neoplasm.

Reference Range *

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Cells must be capable of dividing. Necrotic specimens of those older than 24 hours may not grow. Specimens collected using non-sterile techniques may have microbial contamination.

Test Details
Days Set Up
Monday - Friday, 8:00am - 4:00pm. Call the laboratory at (734) 763-5805 for additional information.
Analytic Time

14-21 days

Soft Order Code
MiChart Code
Cytogenetics, Chromosome Analysis/Karyotype, Solid Tumor (Non-Lymphoma)
  • Chromosome Analysis, Tumor for Malignancy
  • Karyotype, Neoplasm
  • Karyotype, Solid Tumor
  • Karyotype, Mass
Specimen Requirements
Collection Instructions

Specimen transport should be arranged so that the specimen is received by MLabs the same day it is collected. Collect tumor specimen using aseptic technique. Place tissue in Chromosome Media, available from MLabs. Send at room temperature as soon as possible. Do not allow specimen to overheat or freeze. Small or necrotic samples and samples obtained without collection media are considered suboptimal.

Normal Volume
3 cm(3) or larger
Minimum Volume
0.5 cm(3)
Rejection Criteria
Formalin fixed, frozen or grossly contaminated specimens
Additional Information

Appropriate FISH testing will be performed at an additional charge when indicated. FISH testing is available for a number of oncology probes. For additional information on FISH testing and available probes, contact the Cytogenetics Laboratory. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.

CPT Code
88264 Chromosome Analysis, 88239 Tissue Culture
Fee Code
EA038 Chromosome Analysis, EA001 Tissue Culture