Test Overview
Test Methodology

Unstimulated short term cell culture and chromosome analysis. Fluorescence In Situ Hybridization (FISH) when indicated.

Test Usage

Identification of chromosomal abnormalities to assist in classification of malignant tumors. Most malignant neoplasms are associated with genetic changes and the observation of an abnormal cytogenetic clone is consistent with a neoplasm.

Reference Range *

Interpretive report provided.

Test Limitations

Cells must be capable of dividing. Small samples or specimens older than 24 hours may not grow. Specimens collected using non-sterile techniques may have microbial contamination.

Test Details
Days Set Up
Monday - Friday, 8:00am - 4:00pm. If necessary a STAT courier may be arranged for processing a sample on a priority basis. Call the laboratory at 763-5805 for additional information.
Analytic Time

14-21 days

Soft Order Code
MiChart Code
Chromosome Analysis, Malignancy, Fluid
  • Chromosome Analysis, Ascites
  • Chromosome Analysis, CSF
  • Cytogenetics, Effusion
  • Chromosome Analysis for Malignancy, Fluid
  • Karyotype, Neoplasm
  • Karyotype, Spinal Fluid
Specimen Requirements
Collection Instructions

Specimen transport should be arranged so that the specimen is received by MLabs the same day it is collected. Call for a STAT courier if necessary. Collect neoplastic fluid using aseptic technique and place in Chromosome Media, available from MLabs. Send at room temperature as soon as possible. Do not allow specimen to overheat or freeze. Do not allow specimen to overheat or freeze. Samples containing <5 million dividing cells, and samples that are greater than 24 hours old are suboptimal.

Rejection Criteria
Fixed, frozen or grossly contaminated specimens.
Additional Information

Appropriate FISH testing will be performed at an additional charge when indicated. FISH testing is available for a number of oncology probes. For additional information on FISH testing and available probes, contact the Cytogenetics Laboratory. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.

CPT Code
88262 Chromosome Analysis, 88237 Tissue Culture
Fee Code
36526 Chromosome Analysis, 36542 Tissue Culture
NY State Approved