Days Set Up
Monday - Friday, 8:00am - 4:00pm. If necessary a STAT courier may be arranged for processing a sample on a priority basis. Call the laboratory at 763-5805 for additional information.
Analytic Time

7-10 days

MiChart Code
Cytogenetics, Chromosome Analysis, Blood for Malignancy
Soft Order Code

Test Updated:


Chromosome Analysis, Blood for Malignancy
Karyotype, Malignancy
Chromosome Analysis for Hematologic Disorders, Blood

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Find a Requisition

All specimens should be accompanied by a requisition.

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MLabs provides all the supplies necessary for the collection of specimens.

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Test Overview

Test Methodology

Cell culture without mitogen stimulation and chromosome analysis. Fluorescence In Situ Hybridization (FISH) when indicated.

Test Usage

Rule out acquired chromosomal abnormalities in chronic and acute leukemia. If the patient has at least 10% blasts (or a combination of blasts, promyelocytes and myelocytes totaling 10%) a peripheral blood sample may be useful, however, note that a bone marrow sample is preferred.

Reference Range

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Specimen transport should be arranged so that the specimen is received by MLabs the same day it is collected. Call for a STAT courier if necessary. Alert MLabs if T-cell PLL or other T-cell lymphoproliferative disorder is suspected. Patient should not be transfused, leukophoresed, or treated with antileukemic drugs prior to specimen collection. Collect specimen in a green top (sodium heparin) tube. Invert the tube several times to prevent clotting. Send the specimen intact at room temperature as soon as possible. DO NOT CENTRIFUGE. Clotted samples, samples containing <5 million dividing cells, and samples that are greater than 24 hours old are suboptimal.

Normal Volume
5-10 mL whole blood
Minimum Volume
2 mL whole blood; additional specimen may be required for patients with extremely low white cell counts.

Billing Information

CPT Code
88262 Chromosome Analysis, 88237 Tissue Culture
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.