Test Overview
Test Usage

Detection of in utero chromosome abnormalities.

Reference Range *

Interpretive report provided.

Test Details
Days Set Up
Monday - Friday, 8:00am - 4:00pm
Analytic Time

10-14 days

Soft Order Code
CGNAF
MiChart Code
Cytogenetics, Chromosome Analysis/Karyotype, Amniotic Fluid
Synonyms
  • Karyotype, Amniocentesis
  • CGLABEL
  • GENERIC CYTOGENETICS TEST
  • AMNIO
  • AMNIOCENTESIS
  • TCA
  • TISSUE CULTURE-AMNIO
  • CGNAF
Laboratory
Cytogenetics
Section
Cytogenetics
Specimen Requirements
Collection Instructions

Optimal timing for specimen collection is during 15 to 20 weeks of gestation. Draw 20 mL to 25 mL of amniotic fluid in a sterile syringe, discarding the first 2 mL of amniotic fluid. Remove the needle and transfer the specimen to 2 screw-capped, sterile 15-mL clear, conical centrifuge tubes. Send specimen refrigerated. Specimen cannot be frozen.

Rejection Criteria
Gross contamination, positive urine test, or frozen specimen.
Normal Volume
20 mL
Minimum Volume
10 mL
Additional Information

For University of Michigan registered patients, when chromosome analysis is requested to rule out certain conditions such as Turner syndrome (when indicated based on initial diagnosis) or suspected mosaicism, an additional cell count and/or special stains will be performed at an additional charge. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.

Billing
CPT Code
88267 Chromosome Analysis, 88235 Tissue Culture, 88285 Additional Cell Count
Fee Code
36518 Chromosome Analysis, 36541 Tissue Culture, 36552 Additional Cell Count
NY State Approved
No