Test Overview
Test Methodology

Particle Enhanced Immunoturbidimetric Assay (PENIA)

Test Usage

Cystatin C is produced by all nucleated cells at a constant rate and the production rate in humans appears to be constant over the entire lifetime. Elimination from the circulation is almost entirely via glomerular filtration. The serum concentration of Cystatin C is independent of muscle and gender in the age range of 1 to 50 years. It has been proposed that Cystatin C in serum or plasma is a more sensitive marker for GFR and superior to serum creatinine for estimation of GFR. Cystatin C may also be of value as a prognostic marker for acute heart failure.

Reference Range *

2-18 years: 0.50 - 1.25 mg/L; 18-60 years: 0.60 - 1.15 mg/L; >60 years: 0.60 - 1.25 mg/L.

Test Details
Days Set Up
Daily
Analytic Time

2 hours.

Soft Order Code
CYSC
MiChart Code
Cystatin C, Serum
Synonyms
  • CYSC
  • Cystatin C
Laboratory
Chemical Pathology
Section
Automation
Specimen Requirements
Collection Instructions

Collect specimen in a SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. Samples are acceptable for 7 days when stored refrigerated between 2 and 8C.

Alternate Specimen
Red top, Green top tube (lithium heparin )or Lavender (EDTA).
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL serum
Billing
CPT Code
82610
Fee Code
38140
LOINC
33863-2
NY State Approved
No