Sometimes used in the differential diagnosis of hypercalcemia as urinary cyclic AMP excretion is generally elevated in primary hyperparathyroidism. Can also be useful as an adjunct to serum parathyroid hormone measurements, especially in the diagnosis of parathyroid hormone resistance states, such as pseudohypoparathyroidism.
1.3 - 3.7 nmol/dL of glomerular filtrate
Parathyroid suppression (hypoparathyroidism) does not lower urinary cyclic AMP excretion to definately subnormal values.
3 - 10 days
- AMP, Cyclic
- CYCLIC AMP, URINARY EXCRETION
- CYCLIC AMP
- CREATININE, SERUM
- CREATININE, URINE
Both serum and urine are required for this test. Serum must be obtained at time of urine collection. Collect serum in red top or SST tube. Centrifuge, aliquot serum into a plastic container and refrigerate. Collect random urine and freeze.
Test sent to Mayo Medical Laboratories