Test Overview
Test Methodology

Capillary Electrophoresis

Test Usage

Serum protein electrophoresis is an evaluation for monoclonal gammopathies, Waldenstrom's macroglobulinemia, multiple myeloma, liver disease, inflammatory states, nephrotic syndrome, amyloidosis and A1At deficiency disease. Also used for evaluation of low back pain, arthritis, lymphoma, leukemia and anemia. The small bands and minor alterations detected will have different significance depending on the clinical situation.

Reference Range *

Total Protein (age >=12yrs): 6.0 - 8.3 g/dL; Albumin: 3.43 - 4.84 g/dL, Alpha-1 Globulin: 0.21 - 0.44 g/dL, Alpha-2 Globulin: 0.54 - 0.97 g/dL, Beta Globulin: 0.65 - 1.03 g/dL, Gamma Globulin: 0.70 - 1.47 g/dL, Albumin/Globulin Ratio: 0.88 - 2.30. Pathologist interpretation of results provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

24 hours

Soft Order Code
TPECR
MiChart Code
Cryo Follow-up Protein Electro., Ser
Synonyms
    Laboratory
    Chemical Pathology
    Section
    Immunopathology
    Specimen Requirements
    Collection Instructions

    Whole blood must be maintained at 37 degrees C +/- 2 degrees from the time it is collected until serum is separated from the cells. Collect blood in pre-warmed red top tube (serum separator is unacceptable). Immediately place the specimen into a 37 degrees +/- 2 C incubator or water bath. Leave at 37 degrees C until the clot retracts, remove serum from clot, centrifuge at room temperature, and aliquot cell free serum into plastic aliquot tube. Please note on the specimen label that the specimen was processed at 37 degrees C. Keep serum at room temperature until delivered to MLabs. If specimen processing equipment is not available, the patient should have the specimen collected at a Michigan Medicine Taubman Center Blood Draw Station.

    Special Handling

    Place specimen in 37 degrees C Thermos containing a warm pack or waterbath immediately. See Collection Instructions below.

    Normal Volume
    1 mL serum
    Minimum Volume
    0.5 mL serum
    Rejection Criteria
    Specimen not collected in red top tube (SST is not acceptable) and/or not stored and transported in a warm thermos.
    Additional Information

    Test includes a pathologist interpretation of results billed as a separate additional charge. This test is not available without interpretation. In order to provide an accurate interpretation, abnormal results may be followed by serum immunoglobulins, serum immunofixation at an additional charge, and by immunoglobulin free light chains and/or immunoglobulin G subclass 4 at an additional charge, if clinically indicated. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.

    Billing
    CPT Code
    84165
    Fee Code
    30951
    Pro Fee CPT
    84165-26
    Pro Fee Code
    84165
    LOINC
    24351-9
    NY State Approved
    No