Serum protein electrophoresis is an evaluation for monoclonal gammopathies, Waldenstrom's macroglobulinemia, multiple myeloma, liver disease, inflammatory states, nephrotic syndrome, amyloidosis and A1At deficiency disease. Also used for evaluation of low back pain, arthritis, lymphoma, leukemia and anemia. The small bands and minor alterations detected will have different significance depending on the clinical situation.
Total Protein (age >=12yrs): 6.0 - 8.3 g/dL; Albumin: 3.43 - 4.84 g/dL, Alpha-1 Globulin: 0.21 - 0.44 g/dL, Alpha-2 Globulin: 0.54 - 0.97 g/dL, Beta Globulin: 0.65 - 1.03 g/dL, Gamma Globulin: 0.70 - 1.47 g/dL, Albumin/Globulin Ratio: 0.88 - 2.30. Pathologist interpretation of results provided.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Whole blood must be maintained at 37 degrees C +/- 2 degrees from the time it is collected until serum is separated from the cells. Collect blood in pre-warmed red top tube (serum separator is unacceptable). Immediately place the specimen into a 37 degrees +/- 2 C incubator or water bath. Leave at 37 degrees C until the clot retracts, remove serum from clot, centrifuge at room temperature, and aliquot cell free serum into plastic aliquot tube. Please note on the specimen label that the specimen was processed at 37 degrees C. Keep serum at room temperature until delivered to MLabs. If specimen processing equipment is not available, the patient should have the specimen collected at a Michigan Medicine Taubman Center Blood Draw Station.
Place specimen in 37 degrees C Thermos containing a warm pack or waterbath immediately. See Collection Instructions below.
Test includes a pathologist interpretation of results billed as a separate additional charge. This test is not available without interpretation. In order to provide an accurate interpretation, abnormal results may be followed by serum immunoglobulins, serum immunofixation at an additional charge, and by immunoglobulin free light chains and/or immunoglobulin G subclass 4 at an additional charge, if clinically indicated. By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated.