2 - 10 days
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Quantitation and Qualitative Typing Precipitation at 1 Degree C.
Evaluating patients with vasculitis, glomerulonephritis, and lymphoproliferative diseases and evaluating patients with macroglobulinemia or myeloma in whom symptoms occur with cold exposure.
CRYOGLOBULIN: Negative (positives reported as a percent). CRYOFIBRINOGEN: Negative. Quantitation and immunotyping will not be performed on positive cryofibrinogen. An interpretive report will be provided.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Specimens must be maintained at 37 degrees C +/- 2 degrees C from the time they are collected until plasma or serum is separated from the cells.
LAVENDER TOP: Collect specimen in a lavender top tube (plasma gel tube is unacceptable). Blood may be centrifuged immediately in a room temperature centrifuge. If this is not possible, the specimens can be placed in a 37 degrees C waterbath until they can be centrifuged. Specimen should be centrifuged at 37 degrees; ambient is acceptable if 37 degrees is not plausible. Aliquot plasma into a plastic vial. After the plasma is removed, place in the refrigerator; please note on the requisition or as a footnote in the computer that the specimen was processed at 37 degrees C.
RED TOP: Collect specimen in a red top tube (serum separator tube is unacceptable). Within one minute, specimen must be placed into a 37 degrees C +/- 2 degrees C incubator or waterbath. Leave specimen at 37 degrees C until specimen is clotted. Specimen should be centrifuged at 37 degrees; ambient is acceptable if 37 degrees is not plausible. Aliquot serum into a plastic vial. After the serum is removed, place in the refrigerator; please note on the requisition or as a footnote in the computer that the specimen was processed at 37 degrees C.
If the necessary specimen processing equipment is not available, the patient should have the specimen collected at a University of Michigan Taubman Center Blood Drawing station.