Evaluation of renal function
1-4 years: 0.2 - 0.6 mg/dL, 5-11 years: 0.4 - 0.9 mg/dL, 12-150 years, male: 0.7 - 1.3 mg/dL, female: 0.5 - 1.0 mg/dL. Estimated Glomerular Filtration Rates (eGFR) for both an African American and a non-African American individual calculated using the MDRD study equation will be reported with serum creatinine levels ordered alone or as part of a panel for patients aged 18 - 100 years. A GFR estimate between 15 and 59 mL/min for >= 3 months is classified as chronic kidney disease (Stage 3 or 4).
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
The MDRD formula for estimation of GFR (eGFR) was developed in a population of adults with slowly-declining or stable reduced kidney function. The MDRD formula should not be used to predict eGFR in unstable patients or in children. The GFR estimate can be interpreted accurately only during a steady state of creatinine balance. The GFR estimate will overestimate true GFR if serum creatinine is rising (such as in acute kidney failure) and will underestimate true GFR if serum creatinine is declining (such as in resolution of acute kidney failure). The EGFR should not be used for pharmacy drug dosing.
Days Test Performed
Daily, 24 hours
Soft Order Code
GFR (Glomerular Filtration Rate)
Glomerular Filtration Rate (GFR)
EST GLOMERULAR FILTRATION RATE
STAT requests for this test will be performed on a STAT basis (supervisory staff approval is not required).
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Offsite Collection Instructions
Collect specimen in an SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
0.5 mL serum
0.25 mL serum
The Jaffe reaction used for creatinine on the Advia 2400 can exhibit a positive bias or interference with a number of different compounds. The most common are high levels of ascorbic acid and certain cephalosporin antibiotics (Cefpirone, Cefoxitin, Cefazolin, and Cephalothin). Patients may exhibit fairly dramatic changes in serum creatinine (0.5 - 1.0 mg/dL increases) if samples happen to be drawn at peak drug levels.