Days Set Up
Daily, 24 hours
Analytic Time

2 hours

MiChart Code
CK Total and CKMB (TCK)
Soft Order Code

Test Updated:


CK Total and MB Isoenzyme
Creatine Kinase Fractionation
Creatine Phosphokinase Isoenzyme
Total CPK
CK Isoenzymes, MB

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Test Overview

Test Methodology

Chemiluminescent Immunoassay (CLIA)

Test Usage

Evaluation of patients with possible myocardial infarction. Following myocardial infarction, CK-MB levels generally start to rise after 4-6 hours, peak around 20 hours, and return to normal by 48 hours. Thrombolytic therapy can shorten these times considerably.

Reference Range

MB Isoenzyme: 0 - 4.9 ng/mL (if total CK <500 IU/L) or 0.0 - 1.0% (if total CK >=500 IU/L).

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Collect specimen in a light green top plasma separator tube. Centrifuge, aliquot plasma into a plastic vial and refrigerate.

Normal Volume
0.5 mL plasma
Minimum Volume
0.4 mL plasma

Billing Information

CPT Code
82550 CK, 82553 CK-MB
Pro Fee Code
CKMB 13969-1

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.