Evaluation and monitoring of disorders of skeletal and cardiac muscle. Creatine Kinase only is performed. Order CK, Total and MB Isoenzymes (TCK) if reflex testing is desired for CKMB.
Male: 38 - 240 IU/L; Female: 26 - 180 IU/L
- CK Total
- Creatine Phosphokinase
STAT requests for this test will be performed on a STAT basis (supervisory staff approval is not required).
Collect specimen in a green top tube. Centrifuge, aliquot plasma into a plastic vial and refrigerate.
Creatine Kinase (CK) is localized primarily in skeletal muscle, cardiac muscle, and the brain. Serum CK is elevated in all types of muscular dystrophy, viral myositis, polymyositis, and in any disorder where there is destruction of muscle tissue. Following myocardial infarction, total CK activity starts to rise within 4-8 hrs, peaks at 18-30 hrs, and returns to normal levels after 48-60 hrs. With thrombolytic therapy, CK activity rises earlier and faster and returns toward normal levels earlier than noted above.