Chemiluminescent Immunoassay (CLIA)
Establish diagnosis of adrenocortical insufficiency, Addison's disease, adrenocortical hypersecretion, or Cushing's disease. Malfunction of any of the organs in the hypothalamus - pituitary - adrenal cortex axis will result in alteration of cortisol levels.
AM: 7.0 - 22.0 mcg/dL; PM: 3.0 - 13.0 mcg/dL.
Specimen may be stored at room temperature up to 8 hours.
- CORTISOL LEVEL
- Cortisol, IVC
- Cortisol, Right IVC
- Cortisol, Left IVC
- Dexamethasone Suppression Test
Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate up to 48 hours or freeze for longer storage. Circulating cortisol levels follow a diurnal pattern. Cortisol values are the highest in the morning and lowest in the evening. A single analysis of serum cortisol is of little diagnostic value because of daily variation. Blood should be drawn in the morning and late afternoon to evaluate baseline diurnal variation. Indicate time and date of draw on requisition.