Days Set Up
Monday, Wednesday, Friday
Analytic Time

3 - 6 days

MiChart Code
Copper, Liver Tissue
Soft Order Code

Update Type: Reference range changed

Test Updated: 07/29/2020


Cu, Liver Tissue
Wilson's Disease

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Test Overview

Test Methodology

Dynamic Reaction Cell-Inductively Coupled Plasma / Mass Spectrometry (DRC-ICP/MS)

Test Usage

Marked elevations of hepatic copper are characteristic of Wilson's disease (hepatolenticular degeration) and PBC.

Reference Range

Males- 10 - 35 mcg/g dry weight; Females- <50 mcg/g dry wt.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

A minimum of 2 mg of fresh or frozen liver tissue is required for analysis. This is typically a piece of tissue from a 14-gauge needle biopsy at least 0.5 cm long. If an 18-gauge needle is used, the tissue must be at least 1 cm in length. The 18-gauge needle produces a specimen that is thin and fragile and difficult to handle. Fresh or frozen specimen is preferred. Place specimen in a metal free container and refrigerate.

Normal Volume
2 mg fresh or frozen liver tissue
Minimum Volume
2 mg fresh or frozen liver tissue

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.