High-Performance Liquid Chromatography (HPLC) with Electrochemical Detection
Diagnosis of coenzyme Q10 deficiency in mitochondrial disorders; Monitoring patients receiving statin therapy; Monitoring coenzyme Q10 status during treatment of various degenerative conditions including Parkinson and Alzheimer disease.
CoQ10 REDUCED: <18 years: 320 - 1,376 mcg/L; > or =18 years: 415 - 1,480 mcg/L. TOTAL CoQ10: <18 years: 320 - 1,558 mcg/L; > or =18 years: 433 - 1,532 mcg/L. % REDUCED CoQ10: <18 years: 93 - 100%; > or =18 years: 92 - 98%.
3 - 7 days
Collect specimen in a green top tube from a fasting patient (8 hour fast). Place on wet ice immediately. Centrifuge, aliquot plasma into a plastic tube and freeze within 3 hours of collection.
Fasting specimen. Place on wet ice immediately. Must be spun and frozen within 3 hours.
Test sent to Mayo Medical Laboratories.