Test Overview

Test Methodology

Complement Fixation and Immunodiffusion

Test Usage

Establish presence of antibody to Coccidioides.

Reference Range*

Complement Fixation: Negative. If positive, results are titered. Immunodiffusion: Negative.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Antibodies (both IgM and IgG) may persist after the infection has resolved.

Test Details

Days Test Performed

Monday - Friday

Analytic Time

4 - 8 days

Soft Order Code




Fungal Antibody, Coccidioides
San Joaquin Valley Fever

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Laboratory Reference

Mayo SCOC (8295) (serum), Mayo CCOC (81542) (CSF)

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Specimen Requirements

Offsite Collection Instructions

Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. CSF is also acceptable.


Yellow Top Tube

Normal Volume

2.0 mL serum or 2.0 mL CSF

Minimum Volume

1.5 mL serum or 1.2 mL CSF

Additional Information

Test sent to Mayo Medical Laboratories.

Billing Information

Fee Codes

CPT Code

86635 x3

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