Photo-optical clot determination with Factor IX deficient substrate.
Detection of specific coagulation factor IX deficiency.
- Factor IX Assay
- Factor IX:C Assay
- Factor 9 Assay
- Factor 9 Activity
STAT requests for this test will be performed on UMHS inpatients, Emergency Department patients, and Veterans Hospital patients.
Collect specimen in a blue top (citrate 3.2%) tube. Mix by inversion. Specimen should arrive at lab within 3 hours of collection; transport at room temperature. Alternatively, centrifuge, aliquot plasma into a polypropylene plastic vial, and freeze the specimen within 4 hours of collection. Transport frozen specimen on dry ice. Collection of the blood through lines that have been previously flushed with heparin should be avoided. If the blood must be drawn through a VAD (vascular access device), the line should be flushed with 5 mL of saline and the first 5 mL of blood or six dead space volumes of the VAD discarded.
Decreased factor IX may be seen with: Christmas disease (Hemophilia B), liver disease, hypothyroidism, vitamin K deficiency, and Gaucher's disease. Factor IX is increased in patient taking oral contraceptives and during pregnancy.