Test Overview

Test Methodology

Photo-optical clot determination with Factor II deficient substrate.

Test Usage

Detection of specific coagulation factor II deficiency

Reference Range*

50-150%

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Increased in patients taking oral contraceptives. Interpretation of results may be limited if patient is receiving anticoagulant therapy.

Test Details

Days Test Performed

Monday - Friday, one run per day

Analytic Time

1 hour

Soft Order Code

F2

MiChart Code

Factor 2 Assay

Synonyms

Laboratory

Hematopathology

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Specimen Requirements

Offsite Collection Instructions

Collect specimen in a blue top (citrate 3.2%) tube. Mix by inversion. Specimen should arrive at lab within 3 hours of collection; transport at room temperature. Alternatively, centrifuge, aliquot plasma into a plastic vial, and freeze the specimen within 4 hours of collection. Transport frozen specimen on dry ice. Collection of the blood through lines that have been previously flushed with heparin should be avoided. If the blood must be drawn through a VAD (vascular access device), the line should be flushed with 5 mL of saline and the first 5 mL of blood or six dead space volumes of the VAD discarded.

Rejection Criteria

Specimens will be rejected if not properly filled, clotted, grossly hemolyzed, or contaminated with heparin.

Container

Normal Volume

Full 2.7mL tube or 1mL plasma aliquot

Minimum Volume

Full 1.8mL tube or 1mL plasma aliquot

Additional Information

Factor II is decreased with vitamin K deficiency, liver disease, during warfarin therapy, and in association with lupus anticoagulant.

Billing Information

Fee Codes

CPT Code

85210

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