Detection of specific coagulation factor XIII deficiency
- Factor XIII Assay
- Factor 13 Activity
- Factor 13 Assay
- Factor XIII:C Assay
Collect specimen in a blue top (citrate 3.2%) tube. Mix by inversion. Specimen should arrive at lab within 3 hours of collection; transport at room temperature. Alternatively, centrifuge, aliquot plasma into a polypropylene plastic vial, and freeze the specimen within 4 hours of collection. Transport frozen specimen on dry ice. Collection of the blood through lines that have been previously flushed with heparin should be avoided. If the blood must be drawn through a VAD (vascular access device), the line should be flushed with 5 mL of saline and the first 5 mL of blood or six dead space volumes of the VAD discarded.
Decreased factor XIII may be associated with: disseminated intravascular coagulopathy, acute myocardial infarction, severe liver disease, brain infarction, and recurrent first trimester spontaneous abortions.