Test Overview
Test Methodology

Flow Cytometry

Test Usage

Diagnosis of inflammatory demyelinating diseases (IDDs) with similar phenotype to neuromyelitis optica spectrum disorder (NMOSD), including optic neuritis (single or bilateral) and transverse myelitis
Diagnosis of autoimmune myelin oligodendrocyte glycoprotein (MOG)-opathy
Diagnosis of neuromyelitis optica (NMO)
Distinguishing NMOSD, acute disseminated encephalomyelitis (ADEM), optic neuritis, and transverse myelitis from multiple sclerosis early in the course of disease
Diagnosis of ADEM
Prediction of a relapsing disease course

Reference Range *

MOG FACS, S: Negative
NMO/AQP4 FACS, S: Negative

Test Details
Days Set Up
Monday, Tuesday, Thursday
Analytic Time

8 - 12 days

Soft Order Code
Reference Laboratory
Mayo CDS1
Special Testing
Specimen Requirements
Collection Instructions

Patient Preparation: For optimal antibody detection, we recommend blood drawing the specimen before initiation of immunosuppressant medication. Collect specimen in a red top (or SST) tube. Spin, aliquot and send to Specimen Processing in a screw capped plastic tube, refrigerated.

Red Top Tube
Yellow Top Tube
Normal Volume
3 mL
Minimum Volume
2 mL
Additional Information

By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test performed by Mayo Clinic Laboratories

CPT Code
86255 x 2
Fee Code
38139, AA468
Reflex CPT
86256 x 2
NY State Approved