Test Overview
Test Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Test Usage
Therapeutic Drug Monitoring
Reference Range *
Clozapine: >350 ng/mL; Clozapine & Norclozapine: >450 ng/mL.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Test Details
Days Set Up
Monday - Friday
Analytic Time
3 - 5 days
Soft Order Code
CLOZ
MiChart Code
Clozapine (Clozaril), Level
Synonyms
- Clozaril
- CLOZ
- Clozapine, Plasma/Serum
Laboratory
Sendout
Reference Laboratory
Mayo CLZ (61657)
Section
Special Testing
Specimen Requirements
Additional Information
Clozapine is an antipsychotic agent. Peak clozapine concentrations are reached in 1-6 hours following oral dosage. Elimination half-life is 4-16 hours once steady state levels have been reached. Norclozapine has minimal therapeutic activity. Test sent to Mayo Medical Laboratories; performed by Mayo New England.
Billing
CPT Code
80159
Fee Code
32105
LOINC
6896-5