Days Set Up
Monday - Friday (initial IgA test); refer to individual test entries for reflexive testing.
Analytic Time

8 hours (initial IgA test); refer to individual test entries for reflexive testing.

MiChart Code
Celiac Disease, Algorithm
Soft Order Code
CLIAC

Test Updated:

Synonyms

Celiac Panel

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MLabs provides all the supplies necessary for the collection of specimens.

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Test Overview

Test Methodology

Serum IgA (turbidimetric); Transglutaminase IgA/IgG Antibody (Multiplex Flow Immunoassay); Gliadin IgA/IgG Antibody (Multiplex Flow Immunoassay); Endomysial IgA (ELISA)

Test Usage

The Celiac Disease Algorithm is utilized to streamline the serological testing for the diagnosis of celiac disease. The algorithm initially orders a serum IgA. Depending on the IgA result, further testing is reflexively ordered and processed. If the serum IgA is very low (<6 mg/dL), transglutaminase IgG AB (TTGG) and Gliadin IgG AB (GLADG) are automatically performed. If the serum IgA low (>6, but below age matched reference range), transglutaminase IgG and IgA antibody tests (TTGG, TTGA), and Gliadin IgG and IgA antibody tests (GLADG, GLADA) are reflexively performed. If the initial serum IgA result is normal or elevated, transglutaminase IgA AB (TTGA) is performed. If the transglutaminase IgA AB is negative (<15) or positive (>30), no further testing is performed. Testing is complete. If the transglutaminase IgA AB is weakly positive (15-30), endomysial IgA AB (EMA) and gliadin IgA AB (GLADA) testing are reflexively performed.

Reference Range

Refer to individual test entries.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate for 7 days or freeze for longer storage.

Yellow Top Tube
Normal Volume
1.5 mL serum
Minimum Volume
0.75 mL serum

Billing Information

CPT Code
82784
Pro Fee Code
 
LOINC
 

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.