Update Type: Specimen collection or handling and/or storage changed
Test Updated: 12/06/2023
Test Overview
Test Methodology

Affinity Chromatography / Mass Spectrometry

Test Usage

Screening test for congenital disorders of glycosylation. Note that a positive test could be due to a genetic or non-genetic condition. Reports of abnormal results will include recommendations for additional biochemical and molecular genetic studies to more precisely identify the correct form of CDG.

Reference Range *

Transferrin Mono-oligo/Di-oligo Ratio:

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Other conditions such as hereditary fructose intolerance, galactosemia, and liver disease may result in increased levels of carbohydrate deficient transferrin. Relevant clinical information and the indication for the analysis should be provided with the specimen, in particular for nonpediatric patients.

Test Details
Days Set Up
Monday, Thursday
Analytic Time

4 - 7 days

Soft Order Code
MiChart Code
CDT for Congenital Disorders of Glycosylation (Sendout)
  • CDG
  • CDT Congen Disord Glycosylatio
  • Mono-oligosaccharide/Di-oligosaccharide transferrin ratio
  • A-oligosaccharide/Di-oligosaccharide transferrin ratio
Reference Laboratory
Mayo CDG (89891)
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in red top or SST tube. Centrifuge, aliquot serum into a plastic vial and freeze.

Normal Volume
0.1 mL serum
Minimum Volume
0.05 mL serum
Storage Temperature
Frozen preferred, ambient or refrigerated acceptable
Additional Information

Test sent to Mayo Clinic Laboratories.

CPT Code
Fee Code