Test Overview
Test Methodology

Liquid Chromatography - Tandem Mass Spectrometry (LC-MS/MS)

Test Usage

Monitor therapeutic drug level.

Reference Range *

CEPOX: Therapeutic Toxic/Critical
0.4 - 4.0 ug/mL N/A
CBZN:
(single regimen) 8.0 - 12.0 ug/mL >15.0 ug/mL
(multiple regimen) 4.0 - 8.0 ug/mL N/A

The concentration of carbamazepine epoxide is normally 10-40% that of the parent drug, but can be variable. During combination therapy the relative concentration of carbamazepine epoxide to carbamazepine may increase slightly.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday, Wednesday, Friday
Analytic Time

8 hours

Soft Order Code
CEPOX
MiChart Code
Carbamazepine Epoxide
Synonyms
  • Carbamazepine 10,11-epoxide
  • Tegretol
  • Tegretol Epoxide
Laboratory
Chemical Pathology
Section
Drug Analysis
Specimen Requirements
Collection Instructions

Collect blood in a red top tube; do not use SST. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Alternate Specimen
Heparinized (green top) or EDTA (lavender top) plasma acceptable.
Normal Volume
2 mL serum
Minimum Volume
0.3 mL serum
Rejection Criteria
SST tube not acceptable.
Billing
CPT Code
80161
Fee Code
KA036
LOINC
9415-1
NY State Approved
No