Test Overview
Test Methodology

Chemiluminescent Immunoassay (CLIA)

Test Usage

Follow-up management of patients undergoing cancer therapy, especially for ovarian carcinoma. Consistently rising CA 125 results may be associated with malignant disease and poor response to therapy; declining values may be indicative of a favorable response to therapy.

Reference Range *

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

CA 125 concentrations are elevated in 1-2% of healthy individuals and may be elevated in diseases other than ovarian cancer, including benign and malginant disorders. CA 125 is NOT a cancer screening test.

Test Details
Days Set Up
Daily, 24 hours
Analytic Time

4 hours

Soft Order Code
MiChart Code
CA 125
  • Cancer Antigen 125
  • DM70K Replacement Assay
  • Ovarian Cancer Tumor Marker
  • CA125
  • CA 125
Chemical Pathology
Specimen Requirements
Collection Instructions

Collect specimen in an SST or red top tube. Refrigerate and send intact specimen within 8 hours of collection. Alternatively, centrifuge, aliquot serum into a plastic vial and refrigerate up to 48 hours or freeze for longer storage.

Alternate Specimen
Red Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL serum
Additional Information

Tested by a chemiluminescent immunoassay manufactured by Siemens Healthineers, performed on Atellica IM system. Results determined from different manufacturers and/or methods may not be comparable.

CPT Code
Fee Code