Test Overview
Test Methodology

Automated Liposome Lysis Assay

Test Usage

Diagnosis of C9 deficiency; investigation of a patient with absent total complement (CH50) level.

Reference Range *

37 - 61 units/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Saturday
Analytic Time

2 - 4 days

Soft Order Code
C9
MiChart Code
C9 Complement, Functional
Synonyms
    Laboratory
    Sendout
    Reference Laboratory
    Mayo C9FX (81066)
    Section
    Special Testing
    Specimen Requirements
    Collection

    A fasting specimen is preferred but not required. Collect specimen in an SST (preferred) or red top tube. Immediately after drawing specimen, place the tube on wet ice and allow specimen to clot. Centrifuge at 4 degrees C, aliquot serum into a plastic vial and freeze within 30 minutes of collection. (Note: if a refrigerated centrifuge is not available, it is acceptable to use a room temperature centrifuge, provided the sample is kept on ice before centrifugation, and immediately afterward, the serum is aliquoted and frozen).

    Special Handling

    Place sample on wet ice following collection. Must arrive in lab or aliquot and freeze within 30 minutes of collection.

    Fasting Specimen
    A fasting specimen is preferred but not required.
    Normal Volume
    1 mL serum
    Minimum Volume
    0.5 mL serum
    Storage Temperature
    Strict frozen.
    Additional Information

    The Complement, Total Hemolytic (CH50) assay should be used as a screen for suspected complement deficiencies before ordering individual complement component assays. A deficiency of an individual component of the complement cascade will result in an undetectable total complement level. Test sent to Mayo Medical Laboratories.

    Billing
    CPT Code
    86161
    Fee Code
    38143
    NY State Approved
    No