Test Overview
Test Methodology

Automated Liposome Lysis Assay

Test Usage

Diagnosis of C9 deficiency; investigation of a patient with absent total complement (CH50) level.

Reference Range *

37 - 61 units/mL

Test Details
Days Set Up
Monday - Saturday
Analytic Time

2 - 4 days

Soft Order Code
MiChart Code
C9 Complement, Functional
  • C9
  • C9 Complement, Functional
Reference Laboratory
Mayo C9FX (81066)
Special Testing
Specimen Requirements

A fasting specimen is preferred but not required. Collect blood in a red top tube; do not use SST tube. Immediately place on wet ice. Centrifuge, aliquot serum into a plastic vial and freeze immediately. Hemolytic or thawed specimens are unacceptable.

Special Handling

Place specimen on wet ice immediately following collection. Must arrive in lab or aliquot and freeze within 2 hours.

Normal Volume
1 mL serum
Minimum Volume
0.5 mL serum
Rejection Criteria
SST tube not acceptable.
Additional Information

The Complement, Total Hemolytic (CH50) assay should be used as a screen for suspected complement deficiencies before ordering individual complement component assays. A deficiency of an individual component of the complement cascade will result in an undetectable total complement level. Test sent to Mayo Medical Laboratories.

CPT Code
Fee Code
NY State Approved