Test Overview
Test Methodology

Automated Liposome Lysis Assay

Test Usage

Diagnosis of C8 deficiency; investigation of a patient with absent total complement (CH50) level.

Reference Range *

33 - 58 units/mL

Test Details
Days Set Up
Monday - Saturday
Analytic Time

1 - 3 days

Soft Order Code
Reference Laboratory
Mayo C8FX (81065)
Special Testing
Specimen Requirements

A fasting specimen is preferred but not required. Collect blood in a red top tube; do not use SST tube. Immediately place on wet ice. Centrifuge, aliquot serum into a plastic vial and freeze immediately. Hemolytic or thawed specimens are unacceptable.

Special Handling

Place specimen on wet ice immediately following collection. Must arrive in lab or aliquot and freeze within 15 minutes.

Normal Volume
1 mL serum
Minimum Volume
0.5 mL serum
Rejection Criteria
SST tube not acceptable.
Additional Information

The Complement, Total Hemolytic (CH50) assay should be used as a screen for suspected complement deficiencies before ordering individual complement component assays. A deficiency of an individual component of the complement cascade will result in an undetectable total complement level. Test sent to Mayo Medical Laboratories.

CPT Code
NY State Approved