Test Overview
Nephelometry
Investigating an undetectable total complement level and investigating individuals with increased susceptibility to bacterial infections. Patients with C5 deficiency haved a marked increase in the incidence of autoimmune disorders and have increased susceptibility to bacterial infection. Congenital deficiency patients have values near zero.
10.6 - 26.3 mg/Dl
The molecule may be dysfunctional with normal values but with ineffective white cell chemotaxis.
Test Details
2 - 4 days
- Complement C5
- Fifth Component of Complement
- C5CP
- C5 COMPLEMENT, ANTIGEN, SERUM
Specimen Requirements
Collect blood in a red top or SST tube from a fasting patient. Centrifuge, aliquot serum into plastic vial and freeze.
Fasting specimen.
Additional Information
The Complement, Total Hemolytic (CH50) assay should be used as a screen for suspected complement deficiencies before ordering individual complement component assays. A deficiency of an individual component of the complement cascade will result in an undetectable total complement level. Test sent to Mayo Medical Laboratories.