Test Overview
Test Methodology

Nephelometry

Test Usage

Investigating an undetectable total complement level and investigating individuals with increased susceptibility to bacterial infections. Patients with C5 deficiency haved a marked increase in the incidence of autoimmune disorders and have increased susceptibility to bacterial infection. Congenital deficiency patients have values near zero.

Reference Range *

10.6 - 26.3 mg/Dl

Test Limitations

The molecule may be dysfunctional with normal values but with ineffective white cell chemotaxis.

Test Details
Days Set Up
Monday, Wednesday, Friday
Analytic Time

2 - 4 days

Soft Order Code
C5CP
MiChart Code
C5 Complement, Antigen
Synonyms
  • Complement C5
  • Fifth Component of Complement
  • C5CP
  • C5 COMPLEMENT, ANTIGEN, SERUM
Laboratory
Sendout
Reference Laboratory
Mayo C5AG (9266)
Section
Special Testing
Specimen Requirements
Collection Instructions

Collect blood in a red top or SST tube from a fasting patient. Centrifuge, aliquot serum into plastic vial and freeze.

Special Handling

Fasting specimen.

Yellow Top Tube
Normal Volume
1 mL serum
Minimum Volume
0.5 mL serum
Additional Information

The Complement, Total Hemolytic (CH50) assay should be used as a screen for suspected complement deficiencies before ordering individual complement component assays. A deficiency of an individual component of the complement cascade will result in an undetectable total complement level. Test sent to Mayo Medical Laboratories.

Billing
CPT Code
86160
Fee Code
20417
LOINC
4405-4