Days Set Up
Daily, 24 hrs
Analytic Time

2 hours

MiChart Code
C4 Complement
Soft Order Code
C4

Test Updated:

Synonyms

C4
B1E
C4
Complement C4
Fourth Component of Complement
C4 COMPLEMENT

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Test Overview

Test Methodology

Immunoturbidimetric

Test Usage

C4 is decreased when classical pathway of complement is hyperactivated. It is usually decreased in hypergammaglobulinemia, cryoglobulinemia, inborn C4 deficiency, active SLE, serum sickness, SBE, chronic active hepatitis, acute glomerulonephritis and rheumatoid arthritis, as well as in hereditary angioneurotic edema.

Reference Range

Adult: 13-60 mg/dl

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Collect specimen in an SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate up to 48 hours.

Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL serum

Billing Information

CPT Code
86160
Pro Fee Code
 
LOINC
4498-2

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.